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pregnyl 1500 i.u x 1 Amp by Organon

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Price:
$10.00
SKU:
Gonadotrophinum chorionicum
Weight:
10.00 Grams
Shipping:
$90.00 (Fixed shipping cost)
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Product Description

Pregnyl contains human Chorionic Gonadotrophin (hCG) which has luteotrophic (LH) activity.
In the female Pregnyl substitutes the endogenous mid-cycle LH surge to induce the final phase of follicular maturation, leading to ovulation. 
In the male Pregnyl stimulates Leydig cells to promote the production of testosterone.

Maximal plasma hCG levels will be reached in males approximately 6 and 16 hours after a single intramuscular or subcutaneous injection of hCG, respectively and in females after approximately 20 hours. HCG is approximately 80% metabolized, predominantly in the kidneys. Intramuscular and subcutaneous administration of hCG were found to be bioequivalent regarding the extent of absorption and the apparent elimination half-lives of approximately 33 hours. On basis of the recommended dose regimens and elimination half-life, cumulation is not expected to occur.

INDICATIONS FOR WOMEN:

In the female as part of a regimen to induce:

  • Ovulation induction in subfertility due to anovulation or impaired follicle-ripening.
  • Preparation of follicles for puncture in controlled ovarian hyperstimulation programs.
  • Luteal phase support.

INDICATIONS FOR MEN:

In the male:

  • Hypogonadotrophic hypogonadism. Cases of idiopathic dysspermias have also shown a positive response to gonadotrophins.
  • Delayed puberty associated with insufficient gonadotrophic pituitary function.
  • Cryptorchidism, not due to anatomical obstruction.

 

SIDE-EFFECTS AND SPECIAL PRECAUTIONS:

Reactions at the site of injection, such as bruising, pain, redness, swelling and itching, have been reported with the use of urinary gonadotrophin preparations. Occasionally allergic reactions have been reported, mostly manifesting as pain and/or rash at the injection site. In rare cases generalized rash or fever may occur.

 
In the female:

Unwanted ovarian hyperstimulation, ovarian hyperstimulation syndrome. Characteristic symptoms of unwanted ovarian hyperstimulation and the ovarian hyperstimulation syndrome are included above, under "Warnings".
 

In the male:

Water and sodium retention is occasionally seen after administration of high dosages; this is regarded as a result of excessive androgen production.
HCG treatment may sporadically cause gynaecomastia.

 


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